Database : HANSEN
Search on : HIPERSENSIBILIDADE TARDIA [Subject descriptor]
References found : 30 [refine]
Displaying: 1 .. 20   in format [Detailed]

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Id:13414
Author:Closs, O; Kronvall, G
Title:Experimental murine leprosy ..-
Source:s.l; s.n; 1975. 6 p. ilus, tab.
Abstract:Sera from C3H and C57BL mice infected with Mycobacterium lepraemurium (MLM) and from human leprosy patients were examined for antibodies against MLM by a crossed immunoelectrophoresis (CIE) technique. Altogether antibodies against six or seven MLM antigens were found in the mouse sera. After a small inoculum of MLM, C3H mice produced more antibodies than C57BL mice. After a large inoculum both strains produced about the same amount of antibodies but showed qualitative differences in their response patterns. A serum pool from patients with lepromatous leprosy contained antibodies against six MLM antigens; five of these were identical with the antigens against which antibodies were found in infected mice. C57BL mice that had lost their delayed-type hypersensitivity to MLM during the course of a disseminated infection showed a fairly strong antibody response to three antigens and a weak response to three others. Since almost the same spectrum of antibodies, although in lower titres, could be demonstrated in C57BL mice with intact delayed-type hypersensitivity to the bacilli, these antibodies did not seem to interfere with the expression of cell-mediated immunity.(AU).
Descriptors:MODELOS ANIMAIS DE DOENCAS
ANTIGENOS DE BACTERIAS
ANTICORPOS ANTIBACTERIAS
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
IMUNOELETROFORESE BIDIMENSIONAL
HANSENIASE/imunol
CAMUNDONGOS ENDOGÂMICOS C3H/imunol
CAMUNDONGOS ENDOGÂMICOS C57BL/imunol
MYCOBACTERIUM LEPRAEMURIUM/imunol
Limits:HUMANO
ANIMAL
FEMININO
CAMUNDONGOS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00024/s


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Id:13321
Author:Saha, Kunal; Mittal, Mmdan M; Ray, S. N
Title:Consequences of smallpox vaccination in leprosy patients ..-
Source:s.l; s.n; sep. 1973. 8 p. tab.
Abstract:This study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. Results obtained with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy.(AU).
Descriptors:HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
IMUNOGLOBULINA A/anal
IMUNOGLOBULINA G/anal
IMUNOGLOBULINA M/anal
INJECOES INTRADERMICAS
HANSENIASE/imunol
VACINA ANTIVARIOLICA/admin
VACINACAO/ef adv
VIRUS DA VACÍNIA/imunol
FORMACAO DE ANTICORPOS
 CALOR
 HEMAGLUTINACAO
 IMUNIZACAO SECUNDARIA
 INIBICAO (PSICOLOGIA)
 MERCAPTOETANOL
 COMPLEMENTO/anal
 IMUNODIFUSAO
Limits:HUMANO
ADULTO
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01256/s


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Id:13309
Author:Bhide, M. B; Dholam, S. B; Chatterjee, B. R
Title:Inhibition of foot pad multiplication of M. leprae in mice vaccinated with leproma derived M. leprae precursor coccoid organism and passive transfer of DTH response to normal mice through infusion of splenic cells of such vaccinated mice ..-
Source:s.l; s.n; oct. 1981. 8 p. graf.
Abstract:Inhibition of foot pad multiplication of M. leprae in mice vaccinated with leproma derived M. leprae precursor coccoid organism and passive transfer of DTH response to normal mice through infusion of splenic cells of such vaccinated mice.(AU).
Descriptors:VACINAS BACTERIANAS/imunol
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIZACAO PASSIVA
MYCOBACTERIUM LEPRAE/imunol
BACO/transpl
VACINACAO
Limits:ANIMAL
CAMUNDONGOS
SUPPORT, NON-U.S. GOV'T
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00813/s


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Id:13281
Author:Smelt, A. H. M; Rees, R. J. W; Liew, F. Y
Title:Failure to induce delayed-type hipersensivity to Mycobacterium leprae in long-term treated lepromatous leprosy patients ..-
Source:s.l; s.n; jun. 1981. 5 p. tab, graf.
Abstract:Lepromatous leprosy (LL) patients whose bacillary load has decreased to almost undetectable levels by long-term chemotherapy failed to develop delayed-type hypersensitivity (DTH) to Mycobacterium leprae antigen following immunization with killed armadillo-derived m. leprae. When these LL patients were immunized with killed M. leprae in a mixture with live BCG, only DTH to purified protein derivative (PPD) was induced. These results are further evidence that immunological unresponsiveness to the leprosy antigen of patients with lepromatous leprosy is antigen-specific and non-reversible.(AU).
Descriptors:ANTIGENOS DE BACTERIAS/imunol
HIPERSENSIBILIDADE TARDIA
IMUNIZACAO
HANSENIASE/quimioter
HANSENIASE/imunol
MYCOBACTERIUM BOVIS/imunol
MYCOBACTERIUM LEPRAE/imunol
TESTES CUTÂNEOS
Limits:SUPPORT, NON-U.S. GOV'T
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00542/s


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Id:13231
Author:Mustafa, A. S; Talwar, G. P
Title:Delayed hypersensitivity skin reactions to homologous and heterologous antigens in guinea-pigs immunized with M. leprae and four selected cultivable mycobacterial strains ..-
Source:s.l; s.n; oct. 1978. 11 p. tab.
Abstract:Guinea-pigs were immunized with Mycobacterium leprae in saline and with autoclaved preparations of Mycobacterium w., ICRC bacillus, Mycobacterium phlei and Mycobacterium vaccae. A group of animals were also immunized with live Mycobacterium w. All animals were challenged after one month of M. leprae and other mycobacteria. Induration produced in response in guine-pigs to challenge with homologous mycobacterial preparations and M. leprae. In most cases, the early reaction was higher with homologous antigens as compared to M. leprae antigens were however of comparable order especially in animals immunized with Mycobacterium w, and ICRC bacillus. Animals immunized with M. leprae gave low late reactions with preparations from Mycobacterium phlei and Mycobacterium vaccae.(AU).
Descriptors:ANTIGENOS DE BACTERIAS/imunol
ANTIGENOS HETEROFILOS/imunol
HIPERSENSIBILIDADE TARDIA/etiol
TESTES INTRADERMICOS
MYCOBACTERIUM/imunol
MYCOBACTERIUM LEPRAE/imunol
MYCOBACTERIUM PHLEI/imunol
IMUNIZACAO
Limits:ESTUDO COMPARATIVO
HUMANO
ANIMAL
COBAIAS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 02120/s


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Id:13218
Author:Mehra, Vijay; Bloom, Barry R
Title:Induction of cell-mediated immunity to Mycobacterium leprae in guinea pigs ..-
Source:s.l; s.n; mar. 1979. 8 p. ilus, tab.
Abstract:Guinea pigs immunized with intact or disrupted armadillo-grown human Mycobacterium leprae administered in aqueous or oil vehicles were tested with various dilutions of M. leprae suspended in saline, water-soluble M. leprae extract, purified protein derivative, and a water-soluble extract of normal armadillo tissue. The results demonstrated the following. (i) Under no conditions was any skin test reactivity found to normal armadillo tissue extract. (ii) Positive sensitization to both M. leprae and its water-soluble extract was achieved by sensitizing guinea pigs with M. leprae suspended in Hanks solution or saline. Autoclaved M. leprae in Hanks solution or saline inoculated intradermally was an effective immunogen. Oil suspensions or emulsions were effective at sensitization, but appeared to be no better and, in general, slightly weaker, than simple inoculation in aqueous suspension. (iii) Living BCG failed to reveal a significant adjuvant effect on sensitization to M. leprae. However, cord factor appeared to potentiate slightly the sensitization to M. leprae in aqueous suspension. (iv) The minimum dose required for sensitization with M. leprae in aqueous suspension was 55 micrograms of purified bacilli. (v) Animals inoculated with M. leprae in saline or with M. leprae together with BCG showed positive skin test reactivity to the first skin test application made fully 1 year after the initial sensitization. The efficacy of autoclaved, irradiated M. leprae in aqueous, oil-free medium suggests a relatively safe approach to human vaccination studies.(AU).
Descriptors:HANSENIASE/imunol
MYCOBACTERIUM BOVIS/imunol
MYCOBACTERIUM LEPRAE/imunol
TESTES CUTÂNEOS
REACOES CRUZADAS
RELACAO DOSE-RESPOSTA IMUNOLOGICA
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
VACINA BCG
Limits:ANIMAL
COBAIAS
TATUS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 02201/s


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Id:13212
Author:Govil, D. C; Bhutani, L. K
Title:Delayed hypersensitivity skin reactions to lepromin and antigens prepared from four other mycobacteria ..-
Source:s.l; s.n; oct. 1978. 5 p. tab.
Abstract:Antigens prepared from five mycobacteria viz. M. leprae M. vaccae, M. phlei, M.W and ICRC bacillus were used for assessing cross reactivity between different antigens on sixteen patients with different forms of leprosy. ICRC bacillus and M.W gave the best correlation with M. leprae.(AU).
Descriptors:ANTIGENOS DE BACTERIAS/imunol
HIPERSENSIBILIDADE TARDIA/diag
ANTIGENO DE MITSUDA/imunol
HANSENIASE/imunol
HANSENIASE/microbiol
MYCOBACTERIUM LEPRAE/imunol
MYCOBACTERIUM/imunol
MYCOBACTERIUM PHLEI/imunol
Limits:ESTUDO COMPARATIVO
HUMANO
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 02116/s


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Id:12254
Author:Bourée, P; Brette, A. de; Carsalade, G. Y. de
Title:Réaction lépreuse tardive apparue 18 mois après la fin d'un traitement Late reversal leprous reaction appearing 18 months after the termination of treatment-
Source:s.l; s.n; mars 2001. 1 p. .
Descriptors:ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
BIOPSIA
CLOFAZIMINA
CLOFAZIMINA
TINTURAS
SEGUIMENTOS
HIPERSENSIBILIDADE TARDIA
LEPROSTATICOS
LEPROSTATICOS
LEPROSTATICOS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
PREDNISONA
PREDNISONA
PELE
FATORES DE TEMPO
Limits:RELATO DE CASO
Location:BR191.1; 08684/s


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Id:11945
Author:Lockwood, Diana N. J; Colston, M. J; Khanolkar-Young, S. R
Title:The detection of Mycobacterium leprae protein and carbohydrate antigens in skin and nerve from leprosy patients with type 1 (reversal) reactions ..-
Source:s.l; s.n; 2002. 7 p. ilus, tab.
Descriptors:HANSENIASE DIMORFA
HANSENIASE DIMORFA
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
ANTICORPOS ANTIBACTÉRIAS
ANTICORPOS MONOCLONAIS
ANTIGENOS DE BACTÉRIAS
BIOPSIA
CHAPERONINAS
CHAPERONINAS
HIPERSENSIBILIDADE TARDIA
IMUNOHISTOQUIMICA
LIPOPOLISSACARIDIOS
LIPOPOLISSACARIDIOS
MACROFAGOS
NERVOS PERIFÉRICOS
NERVOS PERIFÉRICOS
CÉLULAS DE SCHWANN
PELE
PELE
Location:BR191.1; 08600/s


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Id:11888
Author:Siddiqui, M. Ruby; Moreira, Andre L; Negesse, Yohannes; Taye, Genet A; Hanekom, Willem A; Haslett, Patrick A; Britton, Swen; Kaplan, Gilla
Title:Local nerve damage in leprosy does not lead to an impaired cellular immune response or decreased wound healing in the skin ..-
Source:s.l; s.n; 2002. 6 p. ilus, tab.
Descriptors:HANSENIASE
HANSENIASE
HANSENIASE
ANTIGENOS CD1
ANTIGENOS CD13
ANTIGENOS CD18
BIOPSIA
HIPERSENSIBILIDADE TARDIA
IMUNOHISTOQUIMICA
MYCOBACTERIUM LEPRAE
NEURITE
NEURITE
NEURITE
TESTE TUBERCULINICO
CICATRIZAÇAO DE FERIDAS
Location:BR191.1; 08577/s


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Id:11439
Author:Bourée, P; Brette, A. de; Carsalade, G. Y. de
Title:Réaction lépreuse tardive apparue 18 mois après la fin d'un traitement Late reveral leprous reaction appearing 18 months after the termination of treatment-
Source:s.l; s.n; 2001. 1 p. .
Descriptors:ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
BIOPSIA
CLOFAZIMINA
CLOFAZIMINA
TINTURAS
SEGUIMENTOS
HIPERSENSIBILIDADE TARDIA
LEPROSTATICOS
LEPROSTATICOS
LEPROSTATICOS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
PREDNISONA
PREDNISONA
PELE
FATORES DE TEMPO
Limits:RELATO DE CASO
Location:BR191.1; 08321/s


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Id:11297
Author:Walsh, Douglas S; Villahermosa, Laarni G; Balagon, Maria V; Abalos, Rodolfo M; Fajardo Junior, Tranquilino T; Tan, Esterlina V; Cellona, Roland V; Walsh, Gerald P
Title:Cutaneous delayed-type hypersensitivity responsiveness in lepromatous and borderline lepromatous leprosy patients as determined by Multitest CMI ..-
Source:s.l; s.n; 1999. 9 p. ilus, tab, graf.
Descriptors:ADOLESCENCIA
HIPERSENSIBILIDADE TARDIA
IMUNIDADE CELULAR
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
REPRODUTIBILIDADE DE RESULTADOS
TESTES CUTANEOS
ESTATISTICAS NAO PARAMÉTRICAS
Location:BR191.1; 07236/s


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Id:11034
Author:Yadava, Anjali; Mukherjee, Rama
Title:An immunodominant 30-kDa antigen of a candidate anti-leprosy vaccine, mycobacterium w, shares T and B cell determinants with m. leprae and m. tuberculosis ..-
Source:s.l; s.n; 1993. 11 p. ilus, graf.
Descriptors:HANSENIASE
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM TUBERCULOSIS
ANTIGENOS DE BACTÉRIAS
ANTIGENOS DE BACTÉRIAS
LINFOCITOS B
VACINAS BACTERIANAS
COBAIAS
HIPERSENSIBILIDADE TARDIA
PESO MOLECULAR
LINFOCITOS T
Location:BR191.1; 07213/s


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Id:11016
Author:Triccas, James A; Winter, Nathalie; Roche, Paul W; Gilpin, Andrea; Kendrick, Kathleen E; Britton, Warwick J
Title:Molecular and immunological analyses of the mycobacterium avium homolog of the immunodominant mycobacterium leprae 35-kilodalton protein ..-
Source:s.l; s.n; 1998. 7 p. ilus, tab, graf.
Descriptors:HANSENIASE
MYCOBACTERIUM AVIUM
MYCOBACTERIUM AVIUM
MYCOBACTERIUM LEPRAE
SEQUENCIA DE AMINOACIDOS
SEQUENCIA DE BASES
CLONAGEM MOLECULAR
GENES BACTERIANOS
COBAIAS
PROTEINAS DO CHOQUE TÉRMICO
PROTEINAS DO CHOQUE TÉRMICO
HIPERSENSIBILIDADE TARDIA
EPITOPOS IMUNODOMINANTES
EPITOPOS IMUNODOMINANTES
LEUCOCITOS MONONUCLEARES
TRANSFORMAÇAO LINFOCITICA
DADOS DE SEQUENCIA MOLECULAR
PROTEINAS RECOMBINANTES
HOMOLOGIA DE SEQUENCIA DE AMINOACIDOS
TUBERCULOSE PULMONAR
Location:BR191.1; 07286/s


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Id:10966
Author:Naafs, Ben
Title:Viewpoint: Leprosy after the year 2000 ..-
Source:s.l; s.n; 2000. 4 p. .
Descriptors:HANSENIASE
HANSENIASE
HANSENIASE
LEPROSTATICOS
PELE
CLOFAZIMINA
QUIMIOTERAPIA COMBINADA
HIPERSENSIBILIDADE TARDIA
PREVALENCIA
SAUDE PUBLICA
RIFAMPINA
Location:BR191.1; 07425/s


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Id:10126
Author:Sterne, Jonathan A. C; Fine, Paul E. M; Ponnighaus, Jorg M; Rees, Richard J. W; Chavula, Dominic
Title:Delayede-type hypersensitivity to Mycobacterium leprae soluble antigens as a test for infection with the leprosy bacillus ..-
Source:s.l; s.n; 1998. 9 p. tab, graf.
Descriptors:FATORES EPIDEMIOLOGICOS
FATORES ETARIOS
ADOLESCENCIA
ANTIGENOS DE BACTÉRIAS
HIPERSENSIBILIDADE TARDIA
HANSENIASE
HANSENIASE
HANSENIASE
MALAUI
MYCOBACTERIUM LEPRAE
RAZAO DE DIFERENÇA
FATORES SEXUAIS
TESTES CUTANEOS
Location:BR191.1; 07067/s


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Id:9975
Author:Wang, Xiao-Hong; Ohmen, Jeffrey D; Uyemura, Koichi; Rea, Thomas H; Kronenberg, Mitchell; Modlin, Robert L
Title:Selection of T lymphocytes bearing limited T-cell receptor beta chains in the response to a human pathogen ..-
Source:s.l; s.n; 1993. 5 p. tab, graf.
Descriptors:SEQUENCIA DE AMINOACIDOS
SEQUENCIA DE BASES
HIPERSENSIBILIDADE TARDIA
HANSENIASE
HANSENIASE
DADOS DE SEQUENCIA MOLECULAR
GENES REITERADOS
OLIGODESOXIRRIBONUCLEOTIDIOS
REAÇAO EM CADEIA POR POLIMERASE
RECEPTORES PARA ANTIGENOS DE CÉLULAS T ALFA-BETA
RECEPTORES PARA ANTIGENOS DE CÉLULAS T ALFA-BETA
PELE
LINFOCITOS T
Location:BR191.1; 06619/s


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Id:9968
Author:Sehgal, Virendra N; Bhattacharya, Sambit N; Chattopadhaya, Debasish; Saha, Kunal
Title:Tumor necrosis factor: status in reactions in leprosy before and after treatment ..-
Source:s.l; s.n; 1993. 4 p. tab, graf.
Descriptors:ADMINISTRAÇAO ORAL
ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS NAO ESTEROIDES
CLOROQUINA
CLOROQUINA
CLOROQUINA
CLOFAZIMINA
CLOFAZIMINA
ERITEMA NODOSO
ERITEMA NODOSO
HIPERSENSIBILIDADE TARDIA
HIPERSENSIBILIDADE TARDIA
LEPROSTATICOS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE TUBERCULOIDE
HANSENIASE TUBERCULOIDE
PREDNISOLONA
PREDNISOLONA
COMPRIMIDOS
FATOR DE NECROSE DE TUMOR
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
Location:BR191.1; 06612/s


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Id:9918
Author:Chin-A-Lien, R. A. M; Faber, W. R; Naafs, B
Title:Cyclosporin a treatment in reversal reaction ..-
Source:s.l; s.n; 1994. 2 p. .
Descriptors:HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
QUIMIOTERAPIA COMBINADA
HIPERSENSIBILIDADE TARDIA
HIPERSENSIBILIDADE TARDIA
Limits:HUMANO
RELATO DE CASO
MASCULINO
ADULTO
IDOSO
Location:BR191.1; 06873/s


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Id:9914
Author:Naafs, B
Title:Leprosy reactions: new knowledge ..-
Source:s.l; s.n; 1994. 5 p. ilus, tab.
Descriptors:HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
CITOCINAS
ERITEMA NODOSO
ERITEMA NODOSO
ERITEMA NODOSO
ERITEMA NODOSO
HIPERSENSIBILIDADE TARDIA
HIPERSENSIBILIDADE TARDIA
Location:BR191.1; 06877/s



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